Embarking on a weight loss journey can be a transformative and empowering experience, and at Premium Health, we are excited to offer an innovative solution to support your goals. Contrave® is a prescription medication that, when combined with a reduced-calorie diet and increased physical activity, can help you achieve and maintain a healthier weight. In this blog, we will provide valuable information about Contrave®, its benefits, common side effects, and important considerations to ensure a safe and effective weight loss experience.

Understanding Contrave® for Weight Loss

Contrave is a prescription medication designed to aid weight loss when used in conjunction with a reduced-calorie diet and increased physical activity. Comprising a combination of two FDA-approved drugs, bupropion and naltrexone, Contrave offers a dual-action approach to address weight management challenges. Bupropion, an antidepressant and smoking cessation aid, helps control cravings and supports weight loss by influencing brain pathways associated with appetite and reward. Naltrexone, primarily used to treat alcohol and opioid dependence, complements bupropion’s effects by mitigating the impact of food-related reward signals.

Contrave is intended for use by adults over the age of 18, and its efficacy is enhanced when integrated into a comprehensive weight loss plan. While the medication demonstrates promise in promoting weight loss, it is essential to consider potential side effects and adhere to medical guidelines. Prior consultation with a healthcare professional is crucial to assess individual suitability, address health considerations, and optimize the benefits of Contrave as part of a holistic approach to weight management.

1. Reduced Calorie Diet and Increased Physical Activity:

Contrave® is designed to complement a reduced-calorie diet and increased physical activity. The medication works by helping to control cravings and reduce overall food intake, making it an effective tool for individuals committed to making lifestyle changes.

2. Combination of Medications:

Contrave® is a combination of two FDA-approved medications, bupropion and naltrexone, which work together to target areas in the brain that regulate food intake and energy balance. This dual-action approach sets Contrave® apart as an option for those who may have struggled with weight loss in the past.

3. Suitable for Adults Over 18:

Contrave® is indicated for use in adults over the age of 18. However, it is important to note that individual suitability for this medication is determined by a healthcare professional after a thorough assessment of medical history and overall health.

Common Side Effects and Important Considerations

1. Common Side Effects:

Like any medication, Contrave® may cause side effects. Common side effects include nausea, constipation, headache, vomiting, dizziness, and dry mouth. These side effects are often temporary and tend to improve as the body adjusts to the medication.

2. Serious Side Effects:

While most individuals tolerate Contrave® well, it’s crucial to be aware of potential serious side effects. These may include an increased risk of opioid overdose, visual problems, high blood pressure, heart attack, heart problems or stroke, and eating disorders.

3. Risk of Opioid Overdose:

Contrave® contains naltrexone, which can block the effects of opioid pain medicines. It’s important to inform your healthcare provider if you are taking opioids for pain management to assess the potential risks and benefits of Contrave®.

4. Liver Damage or Hepatitis:

Rare but severe liver damage or hepatitis has been reported in patients taking Contrave®. Monitoring liver function is part of the routine medical supervision during Contrave® therapy.

5. Mental Health Considerations:

Individuals with a history of depression or other mental health conditions should be cautious when using Contrave®. The medication may increase the risk of suicidal thoughts or actions, particularly in the early stages of treatment. It is essential to seek medical attention if you experience symptoms such as depression, anxiety, agitation, panic attacks, irritability, aggression, or changes in behavior or mood.

6. Other Considerations:

Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Contrave® is not recommended for use during pregnancy. Additionally, certain medical conditions and medications may interact with Contrave®, so it’s crucial to provide a comprehensive medical history during consultations.

Safety First: When to Seek Medical Attention

While most individuals can benefit from Contrave® as part of a comprehensive weight loss plan, it is essential to prioritize safety. Seek immediate medical attention if you experience:

  • Thoughts of Suicide: Contrave® may increase the risk of suicidal thoughts, particularly in those with pre-existing mental health conditions.
  • Unusual Changes in Behavior or Mood: Extreme changes in behavior, mood, or activity levels may be indicative of a serious reaction to the medication.
  • Trouble Sleeping: Insomnia or other sleep-related issues may occur, and persistent trouble sleeping should be addressed with a healthcare professional.

In case of severe side effects or adverse reactions, contact your healthcare provider promptly or visit the nearest emergency room.

Taking Contrave® Safely: Important Tips

1. Strict Medication Adherence:

Follow your healthcare provider’s instructions regarding the dosage and schedule of Contrave®. Skipping doses or altering the prescribed regimen may impact the effectiveness of the medication.

2. Regular Medical Check-ups:

Regular check-ups with your healthcare provider are essential to monitor your progress, assess potential side effects, and make any necessary adjustments to your weight loss plan.

3. Lifestyle Changes:

Contrave® is most effective when combined with a reduced-calorie diet and increased physical activity. Embrace lifestyle changes that promote overall well-being and enhance the positive effects of the medication.

4. Stay Hydrated:

Adequate hydration is crucial, especially if you experience common side effects like nausea or constipation. Drinking plenty of water can alleviate these symptoms.

5. Patient Education:

Be well-informed about Contrave® by reading and understanding the full prescribing information, including the medication guide provided with the prescription. This will empower you to make informed decisions about your health.


At Premium Health, we are committed to providing our patients with effective and safe solutions to support their weight loss journey. Contrave® is a valuable addition to our offerings, and its dual-action approach can help individuals achieve their weight loss goals when used in conjunction with a reduced-calorie diet and increased physical activity.

However, it’s essential to approach weight loss with a holistic mindset that includes lifestyle changes, regular medical check-ups, and a commitment to overall well-being. As with any medication, Contrave® should be used under the guidance of a qualified healthcare professional, and individual suitability should be assessed based on a comprehensive evaluation of medical history.

If you are considering Contrave® for weight loss, we encourage you to schedule a consultation with one of our healthcare providers. Together, we can create a personalized plan that aligns with your health goals and sets you on the path to a healthier, more vibrant life.

Please note that the information provided here is for general informational purposes only and should not be considered as medical advice. Always consult with a qualified healthcare professional for personalized guidance based on your specific health needs and circumstances.